Neuroscience
in translational medicine

Statement of Professional Interests: Affective and Cognitive Neuroscience; Biological Psychiatry; Clinical Neurophysiology; High Resolution EEG & ERPs; sMRI & fMRI; EEG/ERP & BOLD co-registration; Neuronal Plasticity; Brain Modulation; Major Depressive Disorder; Anxiety Disorders; PTSD; Schizophrenia; Parkinson Disease; Alzheimer Disease; Brain Fitness; Therapeutic Repetitive Transcranial Magnetic Stimulation; Transcranial Direct and Alter Current Stimulation (tDCS & tACS).

Member of international neuroscience organizations - International Organization of Psychophysiology (IOP), Society for Psychophysiological Researches (SPR, USA), Applied Neuroscience Society (ANS), Society of Biological Psychiatry (SOBP), International Pharmaco-EEG Society, Association for Electrophysiological Brain Research in Preclinical and Clinical Pharmacology and Related Fields, International Society of Electro-Convulsive Therapy and Neurostimulation (ISEN), Honorary Member of the Russsssian Socoety of Psychitrists. Reviewer to International Journal of Psychophysiology, Psychophysiology, Biological Psychology, Brain Researches, Psychosomatic Medicine, World Journal of Biological Psychiatry. Director of the Russian Academy of Science Presidium's program "Affective Neuroscience". Leader of the ENIGMA International Consortium in Russia.

Main research area is related to the study of gene expression regulation in physiological and pathophysiological processes involving nuclear receptors. Alongside above-mentioned research work on the molecular mechanisms of synaptic plasticity underlying learning and memory is also carried out.

In recent years, professor Pokrovsky has been conducting research on searching for and studying compounds with antitumor and antiviral activity. New derivatives of higher terpenoid group having antitumor activity were found. 6 patents for new groups of compounds with antitumor activity were obtained. It has been found that their mechanism of action is associated with the induction of apoptosis in tumor cells. Also, under the supervision of A. G. Pokrovsky the development of safe systems based on pseudoviruses simulating viral infections (filoviruses - Marburg, Ebola, orthomyxoviruses - flu retrovirus - HIV) was carried out. Pseudovirus systems were also used to investigate the mechanism of action of novel compounds having antiviral activity against influenza A virus (H5N1), HIV.

Academic supervisor, International Tomography Center, Siberian Branch of the Russian Academy of Sciences Head of Laboratory "Magnetic Resonance in Chemistry, Biology and Medicine". A leader in the research field of magnetic phenomena in medicine and biology. Lenin Prize (1986), RF State Prize in Science and Technology (1994), the Order of Merit (2002), the Order "For Merit to the Fatherland" IV degree (2007).

Actively engaged in the study of the role of hereditary factors in a variety of human diseases, the development of new methods for molecular genetic studies. Key research areas: molecular genetic basis of multifactorial and hereditary diseases, molecular epidemiological characteristics of the gene pool diversity in the population of North and Central Asia, gene pool evolution in ancient and modern ethnic groups of North Asia, development of methods for molecular genetic analysis of the variability in human genome. Research conducted by Voyevoda contributed significantly to drawing the attention of a large number of researchers in Siberia to genetic problems in human pathology.

Specialist in the field of chemistry of natural compounds, including catalytic conversion of plant metabolites, medicinal chemistry. As a result of research simple and clear schemes to quickly carry out a priori estimate of the desired reaction parameters or characteristics of the molecules under study were suggested. Innovative medicine based on synthetic transformations of plant metabolites were developed.

Is actively engaged in studying the theory and practice of biofeedback, technologies based on the mechanisms of self-regulation of functions. Biofeedback systems created under M. B. Stark leadership are widely represented in the clinics in Russia, CIS countries, Germany, Italy, Spain, Israel, the USA and Malaysia. At this stage, M. B. Stark is developing medical and diagnostic technology of interactive neurostimulation based on the results of noninvasive synergistic brain fMRI, EEG mapping.

Area of interest: research related to the neurophysiology of motor control, regulation of emotional perception, speech recognition, neurophysiological reasons for interindividual differences and the tendency to mental pathologies. Alexander Savostyanov et al studied the EEG correlates of personal anxiety and tendency to depression. In 2013-2016 A. Savostyanov organized scientific expeditions in Siberia and Mongolia to study ethno-cultural characteristics associated with the risk of mental illness in the indigenous population of Siberia. During the expeditions, ethnic differences in the role of molecular genetic markers of the serotonin system in the formation of the level of anxiety and a tendency to depression among the indigenous peoples of Siberia were identified for the first time. During the expedition the EEG research was conducted for the first time to study the features of brain activity in the process of language recognition in the peoples of Siberia and Mongolia. Specificity of EEG reactions in the representatives of the Turkic-speaking peoples were detected associated with the perception of an aggressive and disturbing language in comparison with Russian.

Specialist in the field of magnetic resonance imaging and multislice spiral computed tomography and its applications in medicine and biology. His research interests are related to the development and introduction of new methods of radiation diagnosis and the study of the human cardiovascular system in its natural state and in the state of pathology. Member of the Radiological Society of North America, the (European Society of Radiology, the European Society for Magnetic Resonance in Medicine and Biology.

Research interests lie in the field of human behavior in the face of uncertainty. She is a practicing psychologist, business coach and management consultant. She is the organizer and director of the NSU Interdisciplinary Center for Applied behavior analysis set up to study the problem of autism and help children with autism spectrum disorders as well as to their families.